The Hotel Isaacs Cork is located in the heart of the city, and restaurants, bars, shops, attractions and business addresses are just a short walk away. The hotel is very close to the city's main shopping area on Patrick Street. Other local attractions include St. Finbarre's Cathedral, St Ann's Church at Shandon and Cork City Gaol. Nearby attractions that are easy to access for day trips include Blarney, Kinsale and the Fota House Wildlife Park. Train and bus stations are just a short walk from the Hotel Isaacs Cork. There is a shuttle bus stop providing service to the airport at the hotel's gate.

Each of the 47 guest rooms at the Hotel Isaacs Cork has cable TV, a coffee and tea maker plus direct dial phones. Wireless Internet access is available. Bathrooms include hair dryers and complimentary toiletries.

This hotel is situated in an 1870 Victorian building that has been restored and recently upgraded. It features a heated courtyard garden with a floodlit waterfall. There is a restaurant and bar on site. The Hotel Isaacs Cork has two meeting rooms. Business services and wireless Internet access are available.